Van Thiel D H, Wright H I, Fagiuoli S
Oklahoma Transplant Institute, Baptist Medical Center, Oklahoma City 73112.
Hepatology. 1994 Jul;20(1 Pt 2):20S-23S. doi: 10.1016/0270-9139(94)90268-2.
Because of its importance as an indication for liver transplantation, the epidemiology of chronic hepatitis B disease is presented. Current knowledge relative to the pathobiological mechanisms of hepatitis B virus-related liver disease are presented, followed by a discussion of the treatment modalities currently available for use in hepatitis B virus-related liver disease. This is followed by an examination of their use in both potential transplant recipients and those who have been given liver transplants for hepatitis B virus disease. Finally, a summary of the current status of hepatitis B virus disease and liver transplantation is presented.
由于其作为肝移植指征的重要性,本文介绍了慢性乙型肝炎疾病的流行病学。阐述了目前关于乙型肝炎病毒相关肝病病理生物学机制的知识,随后讨论了目前可用于乙型肝炎病毒相关肝病的治疗方式。接着考察了这些治疗方式在潜在肝移植受者以及因乙型肝炎病毒疾病接受肝移植者中的应用情况。最后,对乙型肝炎病毒疾病和肝移植的现状进行了总结。