Sekhar G C, Vyas P, Nagarajan R, Mandal A K, Gupta S
VST Centre For Glaucoma Care, L.V. Prasad Eye Institute, Hyderabad.
Indian J Ophthalmol. 1993 Dec;41(4):181-4.
To study the risk factors in the development of glaucoma following penetrating keratoplasty, we retrospectively analysed 190 eyes of 185 consecutive patients who had undergone surgery during 1990. The donor button was larger by 0.2 mm and 0.5 mm in phakia and aphakia/pseudophakia patients, respectively. Over a mean follow-up period of 14.5 months, 52 of the 190 eyes (27.4%) either developed glaucoma de novo or had worsening of preexisting glaucoma. Of these 52 eyes, 38 were managed medically and 14 required surgery. From our study, aphakia (37%), pseudophakia (24%), preexisting glaucoma (81.8%), and regrafting (43.18%) were found to be the significant risk factors in the development of glaucoma following penetrating keratoplasty.
为研究穿透性角膜移植术后发生青光眼的危险因素，我们回顾性分析了1990年期间连续接受手术的185例患者的190只眼。有晶状体眼和无晶状体眼/人工晶状体眼患者的植片分别大0.2mm和0.5mm。在平均14.5个月的随访期内，190只眼中有52只（27.4%）新发青光眼或原有青光眼病情加重。在这52只眼中，38只采用药物治疗，14只需要手术治疗。从我们的研究中发现，无晶状体眼（37%）、人工晶状体眼（24%）、原有青光眼（81.8%）和再次移植（43.18%）是穿透性角膜移植术后发生青光眼的显著危险因素。
