Roberge R J, Martin T G, Hodgman M, Benitez J G, Brunswick J E
University of Pittsburgh Medical Center, PA 15213.
J Toxicol Clin Toxicol. 1994;32(3):291-7. doi: 10.3109/15563659409017961.
Baclofen overdose occasionally results in cardiac effects, but serious tachyarrhythmias have not been reported. We present the case of a 21-year-old man with an acute baclofen overdose who developed increased cardiac conduction times and a rapid supraventricular tachyarrhythmia which required medical intervention. Acute baclofen toxicity can result in the development of tachyarrhythmias and cardiac monitoring is warranted in acute overdose states.
巴氯芬过量服用偶尔会导致心脏方面的影响,但严重的快速心律失常尚未见报道。我们报告一例21岁男性急性巴氯芬过量服用病例,该患者出现心脏传导时间延长及快速室上性心律失常,需要进行医学干预。急性巴氯芬中毒可导致快速心律失常的发生,急性过量服用时应进行心脏监测。