Nicolaïdis S
Ann Nutr Aliment. 1976;30(2-3):349-68.
There are appropriate and probably redondant receptors responding to imbalances of either the IC or EC space. Regulation of the EC space seems to evolve different distinct mechanisms for its two components i.e. volemic and interstitial space. They both elicit dipsic and natriophilic responses. Neurophysiology and neurochemistry of dipsic responses to the different types of dehydration is briefly reviewed. Hydromineral homeorheusis (1) can be achieved even without any participation of the orodigestive exteroreceptors, since animals survive without drinking, by self injecting water through an implanted atrial catheter. However, the contribution of exteroreceptors, particularly the oral ones, allow, in ordinary conditions, and even more in exceptionally stressing circumstances, to compensate for all imbalances more rapidly and in a more appropriate and amplified way. So, in everyday's conditions, drinking, in spite of its non-regulatory (i.e. non-triggered by actual imbalances of the inner milieu) appearance, results in an anticipatory and "luxurious" hydromineral regulation. This kind of ingestive behaviour is more adaptive than any behaviour which would tend only to correct imbalances after they happened.
存在对细胞内或细胞外空间失衡做出反应的合适且可能冗余的受体。细胞外空间的调节似乎针对其两个组成部分,即容量空间和间质空间,演化出了不同的独特机制。它们都会引发饮水和嗜钠反应。本文简要综述了对不同类型脱水的饮水反应的神经生理学和神经化学。即使没有口消化道外感受器的任何参与,也能够实现水盐动态平衡(1),因为动物可以通过植入心房导管自行注射水而不饮水存活。然而,外感受器,尤其是口腔外感受器的作用,在正常情况下,甚至在极端应激情况下,能使动物更迅速、更合适且更放大地补偿所有失衡。所以,在日常情况下,尽管饮水看似无调节性(即不是由内环境的实际失衡触发),但它会导致一种预期性的和“奢侈”的水盐调节。这种摄食行为比任何仅在失衡发生后才试图纠正失衡的行为更具适应性。