新型激光断层扫描设备对视神经乳头地形图的可重复性研究。

Reproducibility of the optic nerve head topography with a new laser tomographic scanning device.

作者信息

Rohrschneider K, Burk R O, Kruse F E, Völcker H E

机构信息

Department of Ophthalmology, University of Heidelberg, Germany.

出版信息

Ophthalmology. 1994 Jun;101(6):1044-9. doi: 10.1016/s0161-6420(94)31220-6.

DOI:10.1016/s0161-6420(94)31220-6

PMID:8008345

Abstract

BACKGROUND

Laser scanning tomography has been shown to be an accurate and reliable method for the assessment of the three-dimensional optic disc topography. The authors investigate the reliability of morphometric measurements with the Heidelberg retina tomograph, a new instrument which was designed based on this technology, which simplifies handling and is much smaller than the laser tomographic scanner.

METHODS

Three independent measurements of the optic disc were performed in 39 eyes of 39 patients which were equally divided into the following three groups: glaucoma, glaucoma suspects, and controls.

RESULTS

The mean coefficient of variation for measurement in the glaucoma, glaucoma suspect, and control groups was 2.9%, 5.0%, and 3.4%, respectively, for cup area; 4.9%, 4.6%, and 4.6%, respectively, for cup volume; 5.2%, 3.8% and 3.3%, respectively, for mean cup depth; and 5.2%, 4.1%, and 4.0%, respectively, for maximal cup depth. The mean standard deviation for one pixel of the total image was 30 +/- 6 microns, 28 +/- 7 microns, and 22 +/- 6 microns for the three groups, respectively.

CONCLUSION

The Heidelberg retina tomograph enables fast and reliable measurement of the optic disc topography and therefore may allow exact follow-up of patients.

摘要

背景

激光扫描断层扫描已被证明是评估三维视盘地形图的一种准确可靠的方法。作者研究了使用海德堡视网膜断层扫描仪进行形态测量的可靠性，该仪器是基于这项技术设计的一种新仪器，它简化了操作且比激光断层扫描仪小得多。

方法

对39例患者的39只眼睛进行了视盘的三次独立测量，这些眼睛被平均分为以下三组：青光眼组、青光眼疑似组和对照组。

结果

青光眼组、青光眼疑似组和对照组杯状区域测量的平均变异系数分别为2.9%、5.0%和3.4%；杯状体积分别为4.9%、4.6%和4.6%；平均杯状深度分别为5.2%、3.8%和3.3%；最大杯状深度分别为5.2%、4.1%和4.0%。三组总图像一个像素的平均标准差分别为30±6微米、28±7微米和22±6微米。