Launbjerg J, Fruergaard P, Jacobsen H L, Utne H E, Madsen J K
Hillerød Sygehus, medicinsk afdeling B.
Ugeskr Laeger. 1994 Mar 28;156(13):1945-7, 1950.
In order to perform risk stratification 158 patients with acute chest pain, but without myocardial infarction (non-AMI) underwent exercise 201-thallium scintigraphy at the time of discharge. The patients, of whom 38 (24%) were women, were followed for seven years. The diagnostic sensitivity, specificity and predictive values of the outcome of the examination for identification of patients, who had a cardiac event (cardiac death or later non-fatal AMI) during follow-up, was calculated. Forty-one had a cardiac event during follow-up. The highest sensitivity (85%) was achieved by the combination of transient defect and/or persistent defect and/or abnormal ST-segment response. The highest specificity was provided by a transient defect (90%) and the predictive value of a positive test was 60%-17 of 29 patients with a transient defect had a cardiac event during follow-up. Patients with a normal test had an excellent prognosis, 94% of 82 patients were free of cardiac events during follow-up.
Exercise 201-thallium scintigraphy is suitable for long-term risk stratification in patients with chest pain and suspicion of but unconfirmed myocardial infarction, because high and very low risk subsets can be identified at the time of discharge.
为了进行风险分层,158例急性胸痛但无心肌梗死(非急性心肌梗死)的患者在出院时接受了运动铊-201心肌显像检查。患者中38例(24%)为女性,随访7年。计算了该检查结果对识别随访期间发生心脏事件(心源性死亡或随后的非致命性急性心肌梗死)患者的诊断敏感性、特异性和预测值。41例在随访期间发生了心脏事件。短暂缺损和/或持续缺损和/或ST段反应异常相结合时敏感性最高(85%)。短暂缺损的特异性最高(90%),阳性检查的预测值为60%——29例有短暂缺损的患者中有17例在随访期间发生了心脏事件。检查结果正常的患者预后良好,82例患者中有94%在随访期间无心脏事件。
运动铊-201心肌显像适用于胸痛且怀疑有心肌梗死但未确诊的患者进行长期风险分层,因为在出院时可识别出高风险和极低风险亚组。