非常健康的成年人颞叶体积不存在与年龄相关的差异。
Lack of age-related differences in temporal lobe volume of very healthy adults.
作者信息
DeCarli C, Murphy D G, Gillette J A, Haxby J V, Teichberg D, Schapiro M B, Horwitz B
机构信息
Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, Md. 20892.
出版信息
AJNR Am J Neuroradiol. 1994 Apr;15(4):689-96.
Abstract
PURPOSE
To evaluate age-related differences in temporal and supratemporal brain regions in carefully selected, very healthy men 19 to 92 years of age.
METHODS
MR quantification of brain regions used image segmentation into cerebrospinal fluid and brain matter based on nonlinear modeling of pixel intensity distributions.
RESULTS
There was a significant age-related decrease (approximately 1% per decade) of posterior frontal lobe volume, but not of temporal lobe volume. The mean volume of the right temporal lobe was significantly greater than the left, and this relation did not change with age.
CONCLUSION
In very healthy aging, the volume of the temporal lobes remains constant over the age range of human life.
摘要
目的
评估精心挑选的19至92岁非常健康男性颞叶和颞上脑区的年龄相关差异。
方法
脑区的磁共振定量分析采用基于像素强度分布非线性建模的图像分割方法，将其分为脑脊液和脑实质。
结果
额叶后部体积存在显著的年龄相关减少（每十年约1%），但颞叶体积没有。右侧颞叶的平均体积显著大于左侧，且这种关系不随年龄变化。
结论
在非常健康的衰老过程中，颞叶体积在人类生命的年龄范围内保持恒定。
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