Lafer B, Sachs G S, Labbate L A, Thibault A, Rosenbaum J F
Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114.
Am J Psychiatry. 1994 Jul;151(7):1081-3. doi: 10.1176/ajp.151.7.1081.
The authors investigated the outcome of an alternating time schedule versus two fixed schedules (either morning or evening) of bright light treatment for seasonal affective disorder. The subjects were 31 patients who met DSM-III-R criteria for major depression with a seasonal pattern. No statistically significant difference was observed among patients in the three groups for response criteria after 1 week of treatment. These results support the use of more flexible phototherapy schedules.
作者研究了交替时间安排与两种固定时间安排（早晨或晚上）的强光疗法治疗季节性情感障碍的效果。研究对象为31名符合DSM-III-R标准的季节性重度抑郁症患者。治疗1周后，三组患者在反应标准方面未观察到统计学上的显著差异。这些结果支持采用更灵活的光疗时间表。
