Zlatkov V, Makaveeva V, Zamfirova K
Akush Ginekol (Sofiia). 1993;32(2):21-2.
The study includes 42 pregnant women chosen at random under the age of 20, in their first trimester presented for voluntary termination of pregnancy. Colposcopic, cytologic and histological test was performed. Chronic, often acute, non-specific inflammatory changes were observed, probably connected with early sex life. The establishing of a histologically atypical results in 33.3% of the cases as well as the observation of 21.7% falsely negative results from the colposcopic study support the theory of pregnancy as a factor causing complication for diagnosis. The relatively low sensitivity of the cytology method and 16.7% false negative results none the less the existence of high specificity (100%) is due to coexistence of low-stage dysplasia (I and II stage) and chronic non-specific inflammatory processes and the early, pilot character of the research.
该研究纳入了42名年龄在20岁以下、处于妊娠早期且前来自愿终止妊娠的随机选择的孕妇。进行了阴道镜检查、细胞学检查和组织学检查。观察到慢性的、常为急性的非特异性炎症变化，这可能与过早的性生活有关。33.3%的病例出现组织学非典型结果，以及阴道镜检查中21.7%的假阴性结果，支持了妊娠是导致诊断并发症的一个因素这一理论。细胞学方法相对较低的敏感性以及16.7%的假阴性结果，尽管存在高特异性（100%），是由于低级别发育异常（I级和II级）与慢性非特异性炎症过程并存以及该研究的早期、试点性质。
