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儿童肺动脉自体移植:实现的生长潜力。

Pulmonary autograft in children: realized growth potential.

作者信息

Elkins R C, Knott-Craig C J, Ward K E, McCue C, Lane M M

机构信息

Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City 73190.

出版信息

Ann Thorac Surg. 1994 Jun;57(6):1387-93; discussion 1393-4. doi: 10.1016/0003-4975(94)90089-2.

DOI:10.1016/0003-4975(94)90089-2
PMID:8010778
Abstract

Pulmonary autograft replacement of the aortic valve has the potential to remain viable and grow in proportion to the somatic growth of the child. Changes in aortic annulus and sinotubular dimensions were compared early and late postoperatively, and related to normal. Eighty-six children, 0.9 to 21 years, were operated on between 1986 and 1993: 42 had a root replacement, 24 an inclusion cylinder, and 20 a scalloped subcoronary implant. Actuarial survival at 7 years was 96.5% +/- 2.0%. Freedom from reoperation for the pulmonary autograft or the homograft reconstruction of the right ventricular outflow tract was 92% +/- 4%. Freedom from reoperation on the autograft in root replacements was 96% +/- 4%, in the inclusion cylinder was 100%, and in the scalloped subcoronary was 90% +/- 7% (not significant). Aortic annulus and sinotubular junction diameters were compared with normal values predicted by body surface area. In 22 intraaortic implants, early and late postoperative annulus diameter mean Z values are in the normal range. In the 23 root replacements, early annulus diameter was within the normal range, but late Z values were larger than normal (p < 0.02). Intraaortic implant annulus diameter increased proportionally to somatic growth, but the sinotubular junction, which was small, remained small but increased toward normal. In the root replacements, the annulus increased in diameter and became dilated. The sinotubular junction, which was small early, increased and was within the normal range late. Lower operative risk and valve durability without failure suggest improved results with inclusion cylinder technique.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

主动脉瓣的肺动脉自体移植有可能保持活力,并随着儿童身体的生长而成比例地生长。对术后早期和晚期的主动脉瓣环及窦管交界尺寸进行了比较,并与正常值相关联。1986年至1993年间,对86名年龄在0.9岁至21岁的儿童进行了手术:42例行根部置换术,24例行包裹性柱状移植术,20例行带槽冠状动脉下植入术。7年的精算生存率为96.5%±2.0%。肺动脉自体移植或右心室流出道同种异体移植无需再次手术的比例为92%±4%。根部置换术中自体移植无需再次手术的比例为96%±4%,包裹性柱状移植术为100%,带槽冠状动脉下植入术为90%±7%(无显著差异)。将主动脉瓣环和窦管交界直径与根据体表面积预测的正常值进行比较。在22例主动脉内植入术中,术后早期和晚期的瓣环直径平均Z值均在正常范围内。在23例根部置换术中,早期瓣环直径在正常范围内,但晚期Z值大于正常(p<0.02)。主动脉内植入瓣环直径与身体生长成比例增加,但较小的窦管交界仍较小,但向正常方向增加。在根部置换术中,瓣环直径增加并扩张。早期较小的窦管交界增加,晚期在正常范围内。较低的手术风险和瓣膜耐久性且无故障表明包裹性柱状移植技术的效果有所改善。(摘要截短至250字)

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