Riederer A, Zietz C, Ihrler S, Vogl T
Klinik und Poliklinik für Hals-Nasen-Ohren-Kranke, Universität München.
Laryngorhinootologie. 1994 Apr;73(4):209-14. doi: 10.1055/s-2007-997113.
Benign lymphoepithelial cysts (BLC) are rare disorders of salivary glands (0.6%). In patients infected by HIV, they are seen more often. In comparison to sporadic BLC, the patients are younger, the diameter of the cysts is up to 5 cm and they are often located bilaterally. At the Department of ENT, Head and Neck Surgery of the Ludwig-Maximilians-University, Munich, ten HIV-infected patients (two females) showed lymphoepithelial cysts (six times bilaterally). One of these revealed a metastasis of a small cell neoplasma near the cysts, another patient showed a non-Hodgkin's lymphoma of low grade malignancy (MALT-type), and one patient additionally had bilateral Warthin's tumours. The BLCs were mostly located in the parotid tail. In three cases, the cysts were found on the inferior border of the parotid and once at the submandibular gland. The age ranged from 27 to 71 years (medium 45.7 years). The mode of HIV infection was homosexuality five times, drug abuse twice, heterosexuality once, and blood products once. In two cases, the channel of transmission was unknown. The majority of the patients showed minor HIV illness (CDC II [n = 2]/CDC III [n = 4]); the rest had advanced immunodeficiency (CDC IV [n = 4]). All the cysts were examined by ultrasonography and NMR. According to the clinical findings and the general stage of health, BLCs were either enucleated (n = 8) or a superficial parotidectomy (n = 5) and selective biopsy of lymph nodes (n = 3) suspected to be malignant were performed.(ABSTRACT TRUNCATED AT 250 WORDS)
良性淋巴上皮囊肿(BLC)是唾液腺的罕见疾病(0.6%)。在感染HIV的患者中,其更为常见。与散发性BLC相比,此类患者更年轻,囊肿直径可达5厘米,且常为双侧性。在慕尼黑路德维希 - 马克西米利安大学耳鼻喉科、头颈外科,10例HIV感染患者(2名女性)出现淋巴上皮囊肿(6例为双侧)。其中1例在囊肿附近发现小细胞肿瘤转移,另1例患者表现为低度恶性非霍奇金淋巴瘤(MALT型),还有1例患者另外患有双侧沃辛瘤。BLC大多位于腮腺尾部。3例囊肿位于腮腺下缘,1例位于下颌下腺。年龄范围为27至71岁(平均45.7岁)。HIV感染方式为同性恋5次、药物滥用2次、异性恋1次、输血1次。2例传播途径不明。大多数患者表现为轻度HIV疾病(疾病控制与预防中心II级[n = 2]/疾病控制与预防中心III级[n = 4]);其余患者有严重免疫缺陷(疾病控制与预防中心IV级[n = 4])。所有囊肿均通过超声和核磁共振检查。根据临床发现和总体健康状况,对BLC进行了摘除术(n = 8)或浅叶腮腺切除术(n = 5),并对疑似恶性的淋巴结进行了选择性活检(n = 3)。(摘要截选至250字)