Yamauchi T, Furui S, Irie T, Kusano S
Department of Radiology, National Defense Medical College, Saitama, Japan.
Acta Radiol. 1994 Jul;35(4):335-9.
We have developed an embolizing material consisting of Y-shaped silicone particles for partial splenic embolization. Wide spaces for blood flow are left around the particles when these are lodged in arterial branches. We embolized one kidney in each of 3 dogs with the particles and observed a slowly induced occlusion of renal arterial branches during one month. The particles were also used for partial splenic embolization in 14 patients. The average portion of infarcted spleen tissue 7 days after embolization was 51% calculated from CT images. In 6 patients who had CT both 2 and 7 days after embolization, the average rate of splenic infarction increased from 29% at 2 days to 60% at 7 days. Our patients required analgesics for only 2.3 days on average. The Y-shaped silicone particles by slowly occluding splenic arterial branches produce ischemia in a gradual fashion which may minimize the pain after embolization.
我们研发了一种由 Y 形硅胶颗粒组成的栓塞材料用于部分脾栓塞。当这些颗粒滞留在动脉分支中时，其周围会留下宽阔的血流空间。我们用这些颗粒栓塞了 3 只狗的一侧肾脏，并在一个月内观察到肾动脉分支的缓慢闭塞。这些颗粒还用于 14 名患者的部分脾栓塞。根据 CT 图像计算，栓塞后 7 天梗死脾组织的平均比例为 51%。在栓塞后 2 天和 7 天均进行 CT 检查的 6 名患者中，脾梗死的平均发生率从 2 天时的 29%增加到 7 天时的 60%。我们的患者平均仅需 2.3 天的镇痛药。Y 形硅胶颗粒通过缓慢闭塞脾动脉分支以渐进方式产生缺血，这可能会使栓塞后的疼痛降至最低。
