Hitchcock R J, Duffy P G, Malone P S
Department of Paediatric Urology, Southampton General Hospital, UK.
Br J Urol. 1994 May;73(5):575-9. doi: 10.1111/j.1464-410x.1994.tb07647.x.
To reduce the complications of enterocystoplasty by augmenting the bladder with a megaureter.
Ureterocystoplasty was performed in eight children aged 20 months-15 years. Three had impaired renal function and three were in established chronic polyuric renal failure.
The seven older children were dry by day with clean intermittent catheterization and the youngest, at the age of 3 1/2 years, had a dry interval of 2 h after catheterization. The three children with polyuric renal failure required nocturnal catheterization or were wet at night. The post-operative urodynamics showed a significant improvement in all cases with abolition of detrusor instability in seven patients and a reduction in end filling pressure. Bladder volume increased from a mean of 100 ml (range 45-215) to 311 ml (range 150-450) (P = 0.01). There was no deterioration in renal function.
The early results of ureterocystoplasty compare favourably with those of enterocystoplasty without the risks of long-term metabolic and neoplastic complications.
通过用巨输尿管扩大膀胱来减少肠膀胱扩大术的并发症。
对8名年龄在20个月至15岁的儿童进行输尿管膀胱扩大术。3名患儿肾功能受损,3名处于已确诊的慢性多尿性肾衰竭状态。
7名年龄较大的儿童通过间歇性清洁导尿实现白天无尿,最年幼的患儿3岁半,导尿后有2小时的无尿间歇期。3名患有多尿性肾衰竭的儿童需要夜间导尿或夜间尿床。术后尿动力学显示所有病例均有显著改善,7例患者逼尿肌不稳定消失,终末充盈压降低。膀胱容量从平均100毫升(范围45 - 215毫升)增加到311毫升(范围150 - 450毫升)(P = 0.01)。肾功能无恶化。
输尿管膀胱扩大术的早期结果与肠膀胱扩大术相比具有优势,且无长期代谢和肿瘤并发症的风险。