Fisang C, Hauser S, Müller S C
University of Bonn, Department of Urology, Bonn, Germany.
Aktuelle Urol. 2010 Jan;41 Suppl 1:S50-2. doi: 10.1055/s-0029-1224654. Epub 2010 Jan 21.
Inadequate therapy endangers upper urinary tract function in children with low compliance bladders. We report our approach of increasing bladder compliance using the patients own (mega)-ureter for bladder augmentation.
A total of 8 children underwent ureterocystoplasty. The etiology of bladder non-compliance and the need for augmentation was neurogenic in 5 children, posterior urethral valves in 2 children and in one child the situation after repeated antireflux surgery. In all patients the kidney of the used ureter was functionless. Surgery was done through a transperitoneal approach. After nephrectomy, the renal pelvis and the ureter were spatulated and sutured into the bladder incision. An additional MACE stoma was made in 3 patients, antireflux surgery for the contralateral kidney was necessary in 2 patients and one patient underwent stone removal in the remaining kidney. In 1 patient the ureter was used as a free transplant and was covered by an omental flap. In addition, a simultaneous living donor kidney transplant was performed (case 2).
Bladder capacity and compliance improved significantly in all patients. The function of the ureter which was used as a free transplant showed good clinical results. The longest follow-up is 8 years.
Ureterocystoplasty is a useful and metabolically neutral alternative to bowel segments. In patients with only one functioning kidney and a contralateral megaureter, ureterocystoplasty is the treatment of choice in our institution.
治疗不充分会危及膀胱顺应性低的儿童的上尿路功能。我们报告了一种利用患者自身的(巨大)输尿管进行膀胱扩大术以提高膀胱顺应性的方法。
共有8名儿童接受了输尿管膀胱成形术。膀胱顺应性差的病因及扩大术需求在5名儿童中为神经源性,2名儿童为后尿道瓣膜症,1名儿童为反复抗反流手术后的情况。所有患者中,所用输尿管的肾脏均无功能。手术通过经腹途径进行。肾切除术后,肾盂和输尿管被做成斜面并缝合到膀胱切口中。3名患者额外做了一个MACE造口,2名患者对侧肾脏需要进行抗反流手术,1名患者对剩余肾脏进行了结石清除术。1名患者的输尿管被用作游离移植并被网膜瓣覆盖。此外,同时进行了活体供肾移植(病例2)。
所有患者的膀胱容量和顺应性均显著改善。用作游离移植的输尿管功能显示出良好的临床效果。最长随访时间为8年。
输尿管膀胱成形术是一种有用的、代谢中性的替代肠段的方法。在只有一侧肾脏有功能且对侧有巨大输尿管的患者中,输尿管膀胱成形术是我们机构的首选治疗方法。