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[二尖瓣疾病中的三尖瓣关闭不全与肺动脉高压:一项超声心动图研究]

[Tricuspid insufficiency and pulmonary hypertension in mitral disease: an echocardiographic study].

作者信息

de Gregorio C, Cavalli G, Nicosia S, Magazù A, Oreto G

机构信息

Cattedra di Cardiologia, Università degli Studi, Messina.

出版信息

Cardiologia. 1994 Feb;39(2):113-9.

PMID:8013015
Abstract

Tricuspid valve regurgitation and pulmonary hypertension have been evaluated with echo-color-Doppler technique in 100 patients (80 females and 20 males, mean age 54 years) affected by mitral valve stenosis. Pure mitral stenosis was present in 13 patients; 87 had an associated mitral regurgitation. The severity of mitral valve disease was based on the planimetric and functional (Doppler-derived) evaluation of valvular area. No relationship was found between extent of tricuspid regurgitation and severity of mitral valve disease, whereas pulmonary artery hypertension was significantly related to mitral valve involvement, above all Doppler mean gradient (r: 0.63, p < 0.005) and valvular area (r: -0.52, p < 0.01). The study suggests that in patients with mitral valve disease tricuspid regurgitation is independent of the degree of mitral valve involvement, whereas pulmonary hypertension is related to transvalvular gradient and to mitral valve area, but does not depend on the duration of the disease. This is evident only in patients who maintain the sinus rhythm.

摘要

采用超声彩色多普勒技术对100例二尖瓣狭窄患者(80例女性,20例男性,平均年龄54岁)的三尖瓣反流和肺动脉高压情况进行了评估。13例患者存在单纯二尖瓣狭窄;87例伴有二尖瓣反流。二尖瓣疾病的严重程度基于瓣膜面积的平面测量和功能(多普勒衍生)评估。未发现三尖瓣反流程度与二尖瓣疾病严重程度之间存在关联,而肺动脉高压与二尖瓣受累情况显著相关,尤其是多普勒平均压差(r:0.63,p < 0.005)和瓣膜面积(r:-0.52,p < 0.01)。该研究表明,在二尖瓣疾病患者中,三尖瓣反流与二尖瓣受累程度无关,而肺动脉高压与跨瓣压差和二尖瓣面积有关,但不取决于疾病持续时间。这仅在维持窦性心律的患者中明显。

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