Björne A, Hindfelt B, Havelius U
Department of Neurology, Malmö General Hospital, University of Lund, Sweden.
Headache. 1994 Apr;34(4):230-3. doi: 10.1111/j.1526-4610.1994.hed3404230.x.
The pathophysiology of cluster headache is largely unknown. One important contributing factor may be an abnormal intracranial-extracranial hemodynamic state. A male patient suffered from chronic left-sided cluster headache for about 15 years. After the institution of lithium therapy the symptoms abated. He was completely free from cluster headache for more than 20 years, until the first postoperative day after a thrombo-endarterectomy for symptomatic 70% carotid stenosis. This case report indicates the importance of abrupt carotid hemodynamic changes along with dysfunction of the cephalic sympathetic nervous system in the initiation of cluster headache.
丛集性头痛的病理生理学在很大程度上尚不明确。一个重要的促成因素可能是颅内-颅外血流动力学状态异常。一名男性患者患有慢性左侧丛集性头痛约15年。锂盐治疗后症状减轻。他20多年来完全没有丛集性头痛发作，直到因有症状的70%颈动脉狭窄行血栓内膜切除术术后第一天再次发作。本病例报告表明，颈动脉血流动力学突然改变以及头部交感神经系统功能障碍在丛集性头痛发作中的重要性。
