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[胃肠管在胃及十二指肠溃疡治疗中的应用]

[Use of a gastrointestinal tube in the treatment of gastric and duodenal ulcer].

作者信息

Eramishantsev A K, Timen L Ia, Shertsinger A G, Kitsenko E A, Zhigalova S B

出版信息

Klin Med (Mosk). 1994;72(2):36-8.

PMID:8015240
Abstract

The trial of a gastrointestinal tube in gastroduodenal ulcer indicates its high efficiency for enteral tube feeding in serious ulcer cases and as a therapeutic modality in noncomplicated cases. The tube introduction in 55 patients out of 89 promoted the defect healing within 2-3 weeks, in 30 out of 36 cicatrization occurred on week 3-5. The presence of the tube produced no effect on acid production in the stomach, cicatrization of the ulcer took place without basic therapy in remaining hypo-achlorhydria and hyperchlorhydria. Clinico-endoscopic evidence and data on gastroduodenal motility and evacuation suggest the conclusion on the neuro-reflex mechanism of the tube action which eliminates painful syndrome and motor-evacuatory abnormalities which are believed essential in pathogenesis of peptic ulcer.

摘要

胃肠管在胃十二指肠溃疡中的试验表明,其在严重溃疡病例的肠内管饲中具有高效性,并且在非复杂性病例中可作为一种治疗方式。89例患者中有55例插入胃肠管后,在2至3周内促进了溃疡缺损愈合;36例中有30例在第3至5周出现瘢痕形成。胃肠管的存在对胃酸分泌没有影响,在其余胃酸过少和胃酸过多的患者中,溃疡在未进行基础治疗的情况下发生了瘢痕形成。临床内镜证据以及有关胃十二指肠动力和排空的数据表明,胃肠管作用存在神经反射机制,该机制消除了疼痛综合征以及运动-排空异常,而这些被认为是消化性溃疡发病机制中的关键因素。

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