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[肾移植前后急慢性肾衰竭时胃泌素及胃液分泌的变化]

[Behavior of gastrin and gastric juice secretion in acute and chronic kidney failure before and after kidney transplantation].

作者信息

Wesdorp R I, Falcao H A, Funovics J M, Fischer J E

出版信息

Langenbecks Arch Chir. 1976;Suppl:216-9.

PMID:801560
Abstract

In 50 patients (10 anephric, 10 with chronic renal failure, and 30 with acute renal failure) the correlation was studied between basal PG levels and basal and stimulated gastric acid secretion. a) The mean PG level in all 3 groups was significantly higher than in the control group, with the highest values in the anephric, which decreased to normal after kidney transplantation. b) In the patients with ARF and after transplantation there was a very positive correlation between PG levels and kidney function. c) Hemodialysis decreased PG levels moderately but significantly. d) Gastric acid studies showed in all groups a very low BAO and basal intragastric pH, with a significant release of gastric acid after pentagastrin stimulation, especially in the anephric.

摘要

在50例患者(10例无肾、10例慢性肾衰竭和30例急性肾衰竭)中,研究了基础前列腺素(PG)水平与基础胃酸分泌及刺激后胃酸分泌之间的相关性。a)所有3组的平均PG水平均显著高于对照组,无肾组的值最高,肾移植后降至正常。b)急性肾衰竭患者及移植后,PG水平与肾功能之间存在非常显著的正相关。c)血液透析使PG水平适度但显著降低。d)胃酸研究显示,所有组的基础胃酸分泌量(BAO)和胃内基础pH值都很低,五肽胃泌素刺激后胃酸显著释放,尤其是在无肾组。

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