Vitale G, Linciano M, Salamanca S, Ferrari P
Divisione di Ostetricia e Ginecologia, USSL 9 Presidio Ospedaliero, S. Vito al Tagliamento, Pordenone.
Minerva Ginecol. 1994 Mar;46(3):91-4.
Sixteen patients with genital HPV associated with CIN were treated with electroablation using a diathermic loop and immunomodulation with human beta interferon. Changes in immunological, cyto-histological and clinical parameters were observed pre- and post-treatment. Thirteen cases showed an excellent response. Disease was persistent in three cases. The authors report an improvement, even if statistically non-significant, in some immune parameters and confirm the value of associating physical therapy with immunomodulating treatment.
16例患有与宫颈上皮内瘤变(CIN)相关的生殖器人乳头瘤病毒(HPV)的患者接受了使用透热环的电灼术治疗以及人β干扰素免疫调节治疗。在治疗前后观察免疫、细胞组织学和临床参数的变化。13例显示出极佳的反应。3例疾病持续存在。作者报告称,一些免疫参数有所改善,即使在统计学上无显著意义,并证实了将物理治疗与免疫调节治疗相结合的价值。