Ryzhavskiĭ B Ia, Eremenko I R, Vasil'eva E V, Nagorskaia N V
Probl Endokrinol (Mosk). 1993 Mar-Apr;39(2):39-41.
Five-day progeny of 12 hemi-ovariectomized rats (111 ratlings) and of 9 intact females (81 ratlings) were examined. Hemi-ovariectomy was carried out 1.5-2 months before pairing with intact males. Body, testicle, ovary, adrenal, and brain mass was measured. The number of follicles in the ovaries, the section size of the tortuous seminal canaliculi in the testes, 3 beta-ol-steroid dehydrogenase activity in the adrenocorticocytes of the adrenocortical bundle zone were under study. The findings evidence a higher body mass, brain, testicular, and adrenal mass of the 5-day progeny of ovariectomized rats. Signs of advanced formation of the follicles and great numbers thereof were found in the ovaries. Another finding was a significant elevation of 3 beta-ol-steroid dehydrogenase activity in the cells of the adrenocortical bundle zone. Therefore, 5-day ratlings of the test group presented with signs of advanced physical development of the examined endocrine glands.
对12只半卵巢切除大鼠（111只幼鼠）和9只未切除卵巢的雌性大鼠（81只幼鼠）的5日龄后代进行了检查。半卵巢切除术在与未切除卵巢的雄性大鼠配对前1.5至2个月进行。测量了身体、睾丸、卵巢、肾上腺和脑的质量。对卵巢中的卵泡数量、睾丸中迂曲精小管的切片大小、肾上腺皮质束状带肾上腺皮质细胞中的3β-ol-类固醇脱氢酶活性进行了研究。研究结果表明，卵巢切除大鼠5日龄后代的身体、脑、睾丸和肾上腺质量更高。在卵巢中发现了卵泡提前形成且数量众多的迹象。另一个发现是肾上腺皮质束状带细胞中的3β-ol-类固醇脱氢酶活性显著升高。因此，试验组的5日龄幼鼠表现出所检查内分泌腺提前发育的迹象。
