Iureneev A P, Gerashchenko Iu S, Dubov P B
Ter Arkh. 1994;66(4):9-11.
The analysis of 3-year follow-up and treatment of 33 and 113 hypertensive subjects without and with coronary insufficiency, respectively, suggested the conclusion on an independent role of left ventricular hypertrophy as a risk factor of cardiac complications in hypertensive patients either with or without coronary insufficiency. A high risk of cardial complications can be expected in hypertensive patients without coronary insufficiency, but with systolic pressure above 200 mm Hg, thickness of the left ventricular posterior wall more than 1.3 cm, % delta S under 40. In the presence of coronary insufficiency hypertensive subjects have a high risk of the complications in case of stroke output over 50 ml, sigma max over 340 10(3) din/cm2, left ventricular myocardial mass over 220 g, history of myocardial infarction. No significant correlation was found between arterial pressure reduction due to antihypertensive treatment and development of cardial complications.
对分别为33名无冠状动脉供血不足和113名有冠状动脉供血不足的高血压患者进行的3年随访及治疗分析表明，无论有无冠状动脉供血不足，左心室肥厚作为高血压患者心脏并发症危险因素具有独立作用这一结论成立。预计无冠状动脉供血不足但收缩压高于200 mmHg、左心室后壁厚度超过1.3 cm、% delta S低于40的高血压患者发生心脏并发症的风险较高。存在冠状动脉供血不足时，心输出量超过50 ml、sigma max超过340×10(3) din/cm2、左心室心肌质量超过220 g、有心肌梗死病史的高血压患者发生并发症的风险较高。未发现降压治疗导致的动脉压降低与心脏并发症的发生之间存在显著相关性。
