Kucherenko A G, Markov Kh M, Zokirov N Z, Naumova V I
Urol Nefrol (Mosk). 1994 Mar-Apr(2):45-8.
A study was made of renin-angiotensin-aldosterone system activity and plasmic concentrations of atrial natriuretic peptide (NUP) as well as antidiuretic hormone in children with primary glomerulonephritis. A close relationship was established of these parameters in regulation of water-salt homeostasis. The above systems are involved in pathogenesis of childhood glomerulonephritis. This finding should be considered in development of pathogenetically validated therapy of glomerulonephritis, including introduction of synthetic NUP.
对原发性肾小球肾炎患儿的肾素-血管紧张素-醛固酮系统活性、血浆心房利钠肽（NUP）浓度以及抗利尿激素进行了研究。在水盐稳态调节中确定了这些参数之间的密切关系。上述系统参与儿童肾小球肾炎的发病机制。在制定针对肾小球肾炎的经病理生理学验证的治疗方法时，应考虑这一发现，包括引入合成NUP。
