健康老年人的微量元素血浆水平与免疫功能

Plasmic levels of trace elements and immune functions in the healthy elderly.

作者信息

Licastro F, Morini M C, Chiricolo M, Conte R, Belletti D, Mancini R, Beltrandi E, Casadei-Maldini M, Carpenè E

机构信息

Department of Experimental Pathology, University of Bologna, Italy.

出版信息

J Trace Elem Electrolytes Health Dis. 1993 Dec;7(4):234-6.

PMID:8019154

Abstract

Healthy elderly persons were selected according to an admission protocol which included clinical, hematological and biochemical parameters. Plasmic levels of zinc in these subjects were in the normal range, while plasmic copper was higher than that of young controls. The number of circulating lymphocytes and CD3+ cells was decreased; however, the absolute number of CD4+, CD8b, CD8d, CD20+ and CD57+ cells did not differ from that of controls. A decreased lymphocyte response to PHA in serum-free medium cultures was also observed in the healthy elderly persons.

摘要

根据包含临床、血液学和生化参数的入院方案选择健康老年人。这些受试者的血浆锌水平在正常范围内，而血浆铜高于年轻对照组。循环淋巴细胞和CD3+细胞数量减少；然而，CD4+、CD8b、CD8d、CD20+和CD57+细胞的绝对数量与对照组无差异。在无血清培养基培养中，健康老年人对PHA的淋巴细胞反应也降低。