Sakamoto O, Saita N, Yamasaki H, Tamanoi M, Ando M
First Department of Internal Medicine, Kumamoto University School of Medicine, Japan.
Chest. 1994 Jul;106(1):308-9. doi: 10.1378/chest.106.1.308.
We describe the first reported case (to our knowledge) of pulmonary granulomatosis caused by aspirated green tea. In this case, we found granulomatous alveolitis with lymph follicles, T lymphocytosis with predominantly CD8+ cells in the bronchoalveolar lavage fluids, positive serum precipitin and proliferative response of peripheral blood lymphocytes to the tea infusion, and efficacy of steroid therapy. These results indicate that the pathogenesis of the disease was due to both humoral and cellular immunities to the aspirated green tea.
据我们所知，我们描述了首例因吸入绿茶导致的肺部肉芽肿病病例。在该病例中，我们发现了伴有淋巴滤泡的肉芽肿性肺泡炎、支气管肺泡灌洗液中以CD8+细胞为主的T淋巴细胞增多、血清沉淀素阳性、外周血淋巴细胞对茶浸液的增殖反应以及类固醇治疗的有效性。这些结果表明，该病的发病机制是由于对吸入绿茶的体液免疫和细胞免疫共同作用所致。
