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[重症细菌性炎症疾病患者及康复期患者的铁过载综合征]

[The iron overload syndrome in patients with severe bacterial inflammatory diseases and convalescents].

作者信息

Soboleva M K, Gavalov S M

出版信息

Gematol Transfuziol. 1993 Mar;38(3):21-4.

PMID:8020729
Abstract

In convalescents after and in patients with sepsis, purulent meningoencephalitis, severe pneumonia the study of iron metabolism provided biochemical criteria of iron excess: low serum transferrin against high transferrin iron, elevated ferritin. The risk of hyperferremia rises considerably after blood or erythrocyte transfusions. The liver got affected in the presence of infectious toxicosis. The authors believe it risky to practice uncontrolled administration of iron preparations in subjects recovering from severe bacterial and inflammatory diseases in view of threatening hemochromatosis.

摘要

在康复期患者以及患有败血症、化脓性脑膜脑炎、重症肺炎的患者中,铁代谢研究提供了铁过量的生化标准:血清转铁蛋白降低而转铁蛋白铁升高、铁蛋白升高。输血或输注红细胞后高铁血症风险显著增加。在存在感染性中毒的情况下肝脏会受到影响。鉴于有发生血色素沉着症的风险,作者认为在从严重细菌感染和炎症性疾病中恢复的患者中无节制地使用铁制剂是危险的。

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