Bogdan C J, Maniglia A J, Eliachar I, Katz R L
Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University Hospitals of Cleveland, Ohio 44106.
Head Neck. 1994 Mar-Apr;16(2):127-34. doi: 10.1002/hed.2880160205.
Chondrosarcoma is a rare neoplasm of the larynx with approximately 200 cases reported in the literature. The infrequent occurrence of this neoplasm, and its indolent pattern of growth, can result in a delayed or missed diagnosis, thereby jeopardizing the preservation of laryngeal function. Four cases of chondrosarcoma of the larynx are presented demonstrating the challenges in the diagnosis and management of this neoplasm. Conservation surgery remains the mainstay of therapy aiming towards preservation of the framework and function of the larynx. Two innovative reconstructive techniques are presented which made conservation laryngeal surgery possible in two of the four patients. Indeed, surgical resection with sound oncologic principles must be applied and total laryngectomy may be necessary. On rare occasion radiotherapy may be used, although its value remains controversial.
软骨肉瘤是一种罕见的喉部肿瘤,文献报道约200例。这种肿瘤发病率低,生长缓慢,可能导致诊断延迟或漏诊,从而危及喉功能的保留。本文介绍了4例喉部软骨肉瘤病例,展示了该肿瘤诊断和治疗中的挑战。保留手术仍是旨在保留喉结构和功能的主要治疗方法。介绍了两种创新的重建技术,使4例患者中的2例能够进行保留喉手术。实际上,必须遵循合理的肿瘤学原则进行手术切除,全喉切除术可能是必要的。尽管放疗的价值仍存在争议,但在极少数情况下可能会使用。