恶性雀斑样痣的冷冻手术
Cryosurgery for lentigo maligna.
作者信息
Kuflik E G, Gage A A
机构信息
University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark.
出版信息
J Am Acad Dermatol. 1994 Jul;31(1):75-8. doi: 10.1016/s0190-9622(94)70139-3.
BACKGROUND
The need for treatment of lentigo maligna is related to the cosmetic benefits and to the potential for malignant change. The usual treatment is excision, but often lesional size or location preclude this.
OBJECTIVE
Our purpose was to show that cryosurgery is an effective alternative treatment modality for lentigo maligna.
METHODS
Thirty white patients were treated with cryosurgery. The lesions ranged from 1.3 to 4.5 cm in diameter. Treatment consisted of freezing with liquid nitrogen delivered by open spray.
RESULTS
The lesion recurred in two patients, yielding a recurrence rate of 6.6% during the average follow-up period of 3 years. The two recurrent lesions were successfully re-treated with cryosurgery. Eleven patients observed for more than 5 years showed no recurrence.
CONCLUSION
Cryosurgery provides excellent cosmetic and curative results. These results are favorably comparable to excisional surgery.
背景
恶性雀斑样痣的治疗需求与美容效果以及恶变可能性相关。通常的治疗方法是切除，但病变的大小或位置常常使这种方法无法实施。
目的
我们的目的是表明冷冻手术是治疗恶性雀斑样痣的一种有效替代治疗方式。
方法
对30例白人患者进行了冷冻手术治疗。病变直径范围为1.3至4.5厘米。治疗方法是用开放式喷雾器喷洒液氮进行冷冻。
结果
两名患者的病变复发，在平均3年的随访期内复发率为6.6%。这两个复发病变通过冷冻手术成功进行了再次治疗。11例观察超过5年的患者未出现复发。
结论
冷冻手术具有出色的美容和治疗效果。这些结果与切除手术相比具有优势。
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