Kunimi K, Amano T, Hasegawa T, Morishita H, Uchibayashi T, Ohkawa M
Department of Urology, School of Medicine, Kanazawa University.
Nihon Hinyokika Gakkai Zasshi. 1994 May;85(5):753-9. doi: 10.5980/jpnjurol1989.85.753.
We surveyed 34 patients of transitional cell carcinoma of the upper urinary tract treated with nephroureterectomy with excision of a cuff of bladder or combined with regional lymphadenectomy to investigate the mode of lymph node metastasis and post-operative recurrence. In 8 of 14 patients undergoing nephroureterectomy with excision of a cuff of bladder combined with regional lymphadenectomy, lymph node metastasis was histologically confirmed in the neighbouring lymph node, of which 2 patients showed the skipped lymph node metastasis simultaneously. Subsequent bladder cancer developed in 12 out of 34 patients (35.3%) and the primary tumor showed papillary growth in all patients except for one patient which showed non-papillary growth, but with pR1. During the observation period with the mean of 9.4 months, remote metastases in other organs were detected in 6 patients with invasive primary tumor more than pT2.
我们对34例接受肾输尿管切除术并切除膀胱袖口或联合区域淋巴结清扫术治疗的上尿路移行细胞癌患者进行了调查,以研究淋巴结转移模式和术后复发情况。在14例接受肾输尿管切除术并切除膀胱袖口联合区域淋巴结清扫术的患者中,有8例在邻近淋巴结中经组织学证实有淋巴结转移,其中2例同时出现跳跃性淋巴结转移。34例患者中有12例(35.3%)随后发生膀胱癌,除1例表现为非乳头状生长但为pR1的患者外,所有患者的原发肿瘤均呈乳头状生长。在平均9.4个月的观察期内,6例浸润性原发肿瘤超过pT2的患者检测到其他器官的远处转移。