Castrogiovanni P, Capone M R, Maremmani I, Marazziti D
Institute of Psychiatry, University of Pisa, Italy.
Neuropsychobiology. 1994;29(3):105-7. doi: 10.1159/000119070.
The availability of peripheral markers of the serotonergic system, which appears to play a major role in aggressive behaviour, prompted us to investigate in healthy subjects the possible correlations between platelet 3H-imipramine (3H-IMI) binding or mono-amine-oxidase (MAO) activity and aggression as measured by the Italian version (QTA) of the Buss and Durkee Inventory. The results showed the presence of significant and positive correlations between MAO activity and QTA total scores and the scales of negativism and verbal aggression, and no correlation between 3H-IMI binding parameters and QTA. These findings seem to suggest that perhaps the MAO activity is more linked to the dimension of aggression than is IMI binding.
血清素能系统的外周标志物的可用性，这一系统似乎在攻击行为中起主要作用，促使我们在健康受试者中研究血小板3H-丙咪嗪（3H-IMI）结合或单胺氧化酶（MAO）活性与通过布斯和德克尔量表意大利版（QTA）测量的攻击性之间的可能相关性。结果显示，MAO活性与QTA总分以及消极主义和言语攻击量表之间存在显著正相关，而3H-IMI结合参数与QTA之间无相关性。这些发现似乎表明，MAO活性可能比IMI结合与攻击维度的联系更紧密。
