Pérez-Carpinell J, de Fez M D, Climent V
Departament d'Optica, Facultat Física, Universitat de València, Burjassot, Spain.
Ophthalmic Physiol Opt. 1994 Apr;14(2):115-21. doi: 10.1111/j.1475-1313.1994.tb00098.x.
We tested the colour vision of 72 people with Down's syndrome using the Ishihara test and an anomaloscope. We found that 13 of the subjects, 6 males and 7 females, had defective colour vision according to Pickford's classification. In monocular vision 10 eyes were protan (five simple, three extreme and two deviant), one eye was simple deuteranomalous and the remaining eyes were normal: in binocular vision four of the subjects were protan (two simple and two deviant), two subjects were deutan (one simple and one deviant) and the rest were normal. Many of our subjects had lens opacities, strabismus, nystagmus, hypermetropia, high myopia and astigmatism, confirming literature reports. The contrast sensitivity function measured with the VCTS test showed a considerable loss of low-frequency sensitivity in our subjects compared to a normal population, which was more marked in the more severely impaired subjects.
我们使用石原氏色盲测验和色盲检查镜对72名唐氏综合征患者的色觉进行了测试。我们发现，根据皮克福德分类法，其中13名受试者（6名男性和7名女性）存在色觉缺陷。单眼视力方面，10只眼睛为红色盲（5只单纯型、3只极端型和2只变异型），1只眼睛为单纯绿色异常，其余眼睛正常：双眼视力方面，4名受试者为红色盲（2名单纯型和2名变异型），2名受试者为绿色盲（1名单纯型和1名变异型），其余正常。我们的许多受试者患有晶状体混浊、斜视、眼球震颤、远视、高度近视和散光，这证实了文献报道。与正常人群相比，使用视觉对比敏感度测试仪（VCTS）测量的对比敏感度函数显示，我们的受试者低频敏感度显著下降，在受损更严重的受试者中更为明显。
