von Flüe M, Rothenbühler J M, Helwig A, Beglinger C, Harder F
Departement Chirurgie, Universitätskliniken, Kantonsspital Basel.
Schweiz Med Wochenschr. 1994 Jun 18;124(24):1056-63.
Coloanal reconstruction is a sphincter saving operation following total rectal resection to treat rectal cancer 3 to 11 cm above the dentate line. Total rectal resection in this situation is justified from the oncological and surgical viewpoint because the local recurrence rate and morbidity are not different from the "gold standard", abdominoperineal resection sacrificing the anal sphincter. Although patients undergoing straight coloanal reconstruction preserve continence, they are often disturbed by high stool frequencies and imperative urge. We set out to establish whether construction of a colon-j-pouch could ameliorate the quality of defecation and thus prove useful. In this study the pre- and postoperative results of a pilot study with 4 consecutive patients following colon-j-pouch-anal reconstruction are presented. Perioperatively, 3 of 4 patients suffered from intermittent disturbances of urinary voiding. Sexual function was disturbed in 3 of 4 patients. All patients were completely continent. The preliminary results showed a decreased sphincter pressure at rest of 40 mm Hg (SD: 5) and a normal squeeze pressure. Endoanal ultrasound demonstrated a normal anal sphincter morphology. Pouch compliance yielded 4.7 ml/cm H2O and was better than after straight coloanal reconstruction in the control group (2.8 ml/cm H2O). The stool frequency at 6 months was 3/24 hours without imperative urge. The colon transit time lasted 49 hours and was in the normal range. No pouch evacuation disorders were observed. These results show a minimal morbidity in colon-j-pouch-anal reconstruction with preservation of complete continence in the follow-up time.(ABSTRACT TRUNCATED AT 250 WORDS)
结肠肛管重建术是一种保留括约肌的手术,用于在齿状线以上3至11厘米处进行全直肠切除术后治疗直肠癌。从肿瘤学和手术角度来看,在这种情况下进行全直肠切除是合理的,因为局部复发率和发病率与“金标准”——牺牲肛门括约肌的腹会阴切除术并无差异。尽管接受直结肠肛管重建术的患者保留了控便能力,但他们常常受到高排便频率和急迫便意的困扰。我们着手研究构建结肠J形贮袋是否能改善排便质量,从而证明其有用性。本研究展示了4例连续进行结肠J形贮袋肛管重建术的初步研究的术前和术后结果。围手术期,4例患者中有3例出现间歇性排尿障碍。4例患者中有3例性功能受到干扰。所有患者均完全控便。初步结果显示静息时括约肌压力降低40毫米汞柱(标准差:5),挤压压力正常。肛管超声显示肛门括约肌形态正常。贮袋顺应性为4.7毫升/厘米水柱,优于对照组直结肠肛管重建术后(2.8毫升/厘米水柱)。6个月时排便频率为3次/24小时,无急迫便意。结肠传输时间持续49小时,在正常范围内。未观察到贮袋排空障碍。这些结果表明,结肠J形贮袋肛管重建术的发病率极低,且在随访期间能保持完全控便。(摘要截短于250字)