Pérez Sempere A, Simón R, Martínez Menéndez B, Torres J, Cabello A, Mateos F
Sección de Neurología Infantil, Hospital 12 de Octubre, Madrid.
Neurologia. 1994 May;9(5):188-90.
Skin biopsy is the method of choice for the diagnosis of Lafora's disease. The presence of PAS (+) inclusions characteristic of Lafora's disease has been thought to be more evident in aprocrine glands of the axillary skin than in the duct cells of the eccrine glands. We describe 4 patients with Lafora's disease diagnosed by axilla skin biopsy, confirming the usefulness of this procedure.
皮肤活检是诊断拉福拉病的首选方法。拉福拉病特有的过碘酸雪夫反应(PAS)阳性包涵体,被认为在腋窝皮肤的顶泌汗腺中比在小汗腺的导管细胞中更明显。我们描述了4例经腋窝皮肤活检确诊为拉福拉病的患者,证实了该检查方法的有效性。