一种用于自旋标记研究的中性水溶性加宽剂。

A neutral water-soluble broadening agent for spin-label studies.

作者信息

Burchfield J, Telehowski P, Rosenberg R C, Eaton S S, Eaton G R

机构信息

Department of Chemistry, University of Denver, Colorado 80208.

出版信息

J Magn Reson B. 1994 May;104(1):69-72. doi: 10.1006/jmrb.1994.1054.

DOI:10.1006/jmrb.1994.1054

PMID:8025813

Abstract

Cr(maltolate)3 is proposed as a neutral water-soluble reagent for the broadening of accessible nitroxyl spin labels or spin probes in biological experiments. For situations in which the molecular charge is important, it supplements Cr(oxalate)3(3-), which is somewhat more effective on a molar basis. The interaction of the two reagents with spin-labeled creatine kinase is an example of a case in which the charge of the broadening agent is important.

摘要

三（苹果酸根）铬（Cr(maltolate)3）被提议作为一种中性水溶性试剂，用于在生物实验中拓宽可及的硝酰自由基自旋标记物或自旋探针。对于分子电荷很重要的情况，它补充了三（草酸根）铬（III）（Cr(oxalate)3(3-)），后者在摩尔基础上效果稍好一些。这两种试剂与自旋标记的肌酸激酶的相互作用就是拓宽剂电荷很重要的一个例子。