Jones R N
Department of Pathology, University of Iowa College of Medicine, Iowa City 52242.
J Clin Microbiol. 1994 Apr;32(4):1104-6. doi: 10.1128/jcm.32.4.1104-1106.1994.
FK-037, a new parenteral cephalosporin, was tested against 483 organisms from clinical infections to establish preliminary susceptibility testing criteria with 30-micrograms disks. The proposed breakpoint zone diameters were > or = 17 mm (MIC correlate, < or = 8 micrograms/ml) for the susceptible category and < or = 13 mm (MIC correlate, > or = 32 micrograms/ml) for the resistant category. These interpretive guidelines produced no very major (false-susceptible) errors, 2.9% major (false-resistant) errors, and 6.2% minor errors for a total absolute agreement between methods of 90.9%.
新型肠胃外头孢菌素FK-037针对483株临床感染分离菌进行了测试，以确立30微克纸片法的初步药敏试验标准。对于敏感类别，建议的折点抑菌圈直径为≥17毫米（对应的最低抑菌浓度，≤8微克/毫升）；对于耐药类别，为≤13毫米（对应的最低抑菌浓度，≥32微克/毫升）。这些解释性指南产生的极重大（假敏感）错误为零，重大（假耐药）错误为2.9%，次要错误为6.2%，两种方法之间的总绝对符合率为90.9%。
