Domzał T, Małowidzka-Serwińska M, Mróz K
Kliniki Neurologicznej CSK WAM, Warszawie.
Neurol Neurochir Pol. 1994 Jan-Feb;28(1):27-34.
The aim of the study was electrophysiological recording of sleep in patients after damage to the right or left cerebral hemisphere after stroke. The studied material comprised 15 patients ages 45 to 75 years, ten of whom had ischaemic stroke in the area of vascularization of the middle cerebral artery as confirmed by CT. In 5 cases the left and in 5 the right hemisphere was damaged. Five patients without organic brain changes served as controls. Sleep study was carried out 4 weeks after stroke, the patients were EEG-monitored during 9 hours of sleep. In stroke patients disruption of the normal pattern of EEG during sleep was found, with absence of sleep cycles and disturbed sequence of these stages. Changes were noted also in the durations of stages N-REM, REM, WASO. In left hemisphere damage the duration of N-REM was shorter, and that of REM was longer than in cases with right hemisphere damage and in controls. After stroke the per cent proportion of the first stage of sleep N-REM was higher mainly in right-sided lesions, while the per cent proportions of stages II and III + IV were lower than in controls. The latency of sleep onset and onset of the first REM was evidently shorter after stroke.
本研究的目的是对中风后右侧或左侧大脑半球受损患者的睡眠进行电生理记录。研究材料包括15名年龄在45至75岁之间的患者,其中10名经CT证实患有大脑中动脉血管化区域的缺血性中风。5例患者左侧半球受损,5例右侧半球受损。5名无器质性脑改变的患者作为对照。中风后4周进行睡眠研究,患者在9小时睡眠期间接受脑电图监测。在中风患者中,发现睡眠期间脑电图的正常模式受到干扰,睡眠周期缺失且这些阶段的顺序紊乱。还注意到N-REM期、REM期、觉醒期的时长有变化。与右侧半球受损患者和对照组相比,左侧半球受损时N-REM期的时长较短,REM期的时长较长。中风后,主要在右侧病变中,睡眠第一阶段N-REM期的百分比更高,而第二阶段和第三+第四阶段的百分比低于对照组。中风后睡眠开始和首次REM开始的潜伏期明显缩短。