Beljanski M M, Bourgarel P, Beljanski M S
C R Acad Hebd Seances Acad Sci D. 1978 Jun 19;286(24):1825-8.
Under well defined conditions ribosomal RNAs purified from Escherichia coli can be degraded by ribonuclease U2 giving rise to RNA fragments of 60--70 nucleotides. In vitro, these fragments are efficiently transcribed into a complementary DNA by DNA polymerase RNA dependent, partially purified from extracts of E. coli. In vivo, "RNA-fragments-U2" inhibit the development of plant tumors.
在明确的条件下,从大肠杆菌中纯化的核糖体RNA可被核糖核酸酶U2降解,产生60 - 70个核苷酸的RNA片段。在体外,这些片段可被从大肠杆菌提取物中部分纯化的依赖RNA的DNA聚合酶有效地转录成互补DNA。在体内,“RNA片段 - U2”可抑制植物肿瘤的生长。