Hiromura T
Department of Radiology, Hokkaido University School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1994 May 25;54(6):500-9.
Retrospectively the ultrasonographic findings of 153 surgically resected cystic thyroid nodules were reviewed. The pathologic findings in this series revealed that 86% were degenerating benign adenomas or adenomatous goiters, and 14% were malignant tumors. The sonographic appearance of these lesions was classified into 7 groups as follows: type I: entirely cystic (less than 1cm), type II: cystic(more than 1cm) [II(a)], and with small polyp or dome-like elevation on the cyst wall [II(b)], type III: larger cyst with projection (more than 1cm) into the lumen, type IV: cyst with a peripherally localized solid component, type V: irregularly mixed cystic and solid components, type VI: a solid mass with multiple crescentic cysts [VI(a)], or round cysts [VI(b)], type VII: a solid mass with only one or two cysts. Pathologic correlation revealed that malignancy in this series ranged from 80% in type III and V to only 4% in type II, where most of the lesions in this group were composed of granulation tissue in degenerating adenomatous polyps and cyst walls. Lesions in type IV showed malignancy rate of 40%. Type III showed characteristic sonographic findings seen in cystic papillary carcinomas (CPCs), with multiple punctate echogenic foci in large pedunculated projections. The typical psammomatous calcifications specific in this group were confirmed in 6 of the 8 type III CPCs. The multiple crescentic cysts in type VI(a) lesions were characteristic sonographic signs seen in adenomatous goiters, representing the pathologic finding of cysts forming around each of multiple adenomatous nodules in this group. Type VII represented non specific appearing lesions, included adenomas, adenomatous goiters, CPCs and follicular carcinomas.(ABSTRACT TRUNCATED AT 250 WORDS)
回顾性分析153例经手术切除的甲状腺囊性结节的超声检查结果。该系列病例的病理检查结果显示,86%为退行性变的良性腺瘤或腺瘤性甲状腺肿,14%为恶性肿瘤。这些病变的超声表现分为以下7组:I型:完全囊性(小于1cm);II型:囊性(大于1cm)[II(a)],囊壁有小息肉或圆顶状隆起[II(b)];III型:较大囊肿,有突入囊腔的凸起(大于1cm);IV型:囊肿周边有局限性实性成分;V型:囊实性成分不规则混合;VI型:实性肿块伴有多个新月形囊肿[VI(a)]或圆形囊肿[VI(b)];VII型:实性肿块仅伴有一两个囊肿。病理相关性分析显示,该系列中恶性病变的比例在III型和V型中为80%,在II型中仅为4%,该组中的大多数病变由退行性变的腺瘤性息肉和囊壁中的肉芽组织组成。IV型病变的恶性率为40%。III型表现出囊性乳头状癌(CPC)的特征性超声表现,在大的带蒂凸起中有多个点状回声灶。在8例III型CPC中,有6例证实了该组特有的典型砂粒体钙化。VI(a)型病变中的多个新月形囊肿是腺瘤性甲状腺肿的特征性超声表现,代表该组中多个腺瘤性结节周围形成囊肿的病理表现。VII型代表非特异性表现的病变,包括腺瘤、腺瘤性甲状腺肿、CPC和滤泡癌。(摘要截断于250字)