Lowkis B, Szymonowicz M
Institute of Electrical Engineering Fundamentals, Technical University of Wrocław.
Polim Med. 1993;23(3-4):15-9.
The paper presents the results of research into the effect of the size and depth of the implanted electric charge on the adhesion of human blood platelets. The experiments were carried out on polyethylene terephthalate PET foil of 36 microns thickness. The electret formation process was carried out in an electron-beam device. The electrization conditions were such that electrets with the excess electric charge accumulated at various depths were obtained. The selection of conditions was verified by investigating the space charge distribution with the use of the virtual electrode method. The microscopic observation of non-electrified foils and electrets as well as the quantitative examination of the adhesion of human blood platelets has explicitly confirmed the positive influence of the electret effect on the thrombogenesis of PET foil. This made it possible to define the optimum electrization conditions. The research has additionally indicated that the relationship between the amount of adherent blood platelets and the size of the electric charge is not a simple relation of the kind: the larger negative charge, the more thrombogenic material. The decisive and positive effect of the space charge has been confirmed by analysing the effectiveness of the surface and space charge.
本文介绍了关于植入电荷的大小和深度对人体血小板粘附影响的研究结果。实验在厚度为36微米的聚对苯二甲酸乙二醇酯（PET）箔上进行。驻极体形成过程在电子束装置中进行。充电条件使得在不同深度积累有过量电荷的驻极体得以获得。通过使用虚拟电极法研究空间电荷分布来验证条件的选择。对未带电箔和驻极体的微观观察以及对人体血小板粘附的定量检测明确证实了驻极体效应在PET箔血栓形成方面的积极影响。这使得确定最佳充电条件成为可能。该研究还表明，粘附血小板数量与电荷大小之间的关系并非简单的如下关系：负电荷越大，血栓形成物质就越多。通过分析表面电荷和空间电荷的有效性，证实了空间电荷具有决定性的积极作用。
