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表现为病理性骨折的骨软斑病

Malakoplakia of bone presenting as a pathological fracture.

作者信息

Tyagi N, Sherwani R, Sadiq S A, Maheshwari V, Abbas M, Tyagi S P

机构信息

Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, India.

出版信息

Postgrad Med J. 1994 Jun;70(824):461-2. doi: 10.1136/pgmj.70.824.461.

DOI:10.1136/pgmj.70.824.461
PMID:8029173
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2397725/
Abstract

A male aged 54 years presented with a pathological fracture of the right femur at the subtrochanteric level. The fracture site showed a lytic lesion with expansion of the bone, considered to be a metastasis. On histology, however, the area turned out to be malakoplakia of bone. The patient responded well to antibiotics and sulphonamides along with skeletal traction. This appears to be the fourth reported case of malakoplakia of bone.

摘要

一名54岁男性因右股骨转子下水平病理性骨折就诊。骨折部位显示有骨质溶解病变且伴有骨质膨胀,考虑为转移瘤。然而,组织学检查结果显示该区域为骨软斑病。患者接受抗生素、磺胺类药物治疗及骨骼牵引后恢复良好。这似乎是第四例报告的骨软斑病病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a2/2397725/0629ce252586/postmedj00042-0073-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a2/2397725/aa3f5bb545a0/postmedj00042-0072-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a2/2397725/08b8d09f34c4/postmedj00042-0073-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a2/2397725/04379260e13e/postmedj00042-0073-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a2/2397725/0629ce252586/postmedj00042-0073-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a2/2397725/aa3f5bb545a0/postmedj00042-0072-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a2/2397725/08b8d09f34c4/postmedj00042-0073-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a2/2397725/04379260e13e/postmedj00042-0073-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a2/2397725/0629ce252586/postmedj00042-0073-c.jpg

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Malakoplakia of Proximal Tibia- A Case Report.胫骨近端软斑病——病例报告
J Orthop Case Rep. 2014 Apr-Jun;4(2):78-80. doi: 10.13107/jocr.2250-0685.174.

本文引用的文献

1
MALACOPLAKIA OF THE URINARY TRACT: A STUDY OF TWENTY-FOUR CASES.泌尿道软斑症:24例病例研究
Am J Clin Pathol. 1965 May;43:409-17. doi: 10.1093/ajcp/43.5.409.
2
Malacoplakia of bone: a case report.骨软斑病:一例报告
J Bone Joint Surg Br. 1981 Aug;63-B(2):254-6. doi: 10.1302/0301-620X.63B2.7217151.
3
Malacoplakia: a study of the literature and current concepts of pathogenesis, diagnosis and treatment.软斑病:文献综述及发病机制、诊断与治疗的当前概念
J Urol. 1981 Feb;125(2):139-46. doi: 10.1016/s0022-5347(17)54940-x.
4
The ultrastructural features of malakoplakia.
J Pathol. 1981 May;134(1):13-25. doi: 10.1002/path.1711340104.
5
Autopsy findings in a unique case of malacoplakia. A cytoimmunohistochemical study of Michaelis-Gutmann bodies.一例特殊的软化斑尸检结果。对迈克尔is -古特曼小体的细胞免疫组织化学研究。
Arch Pathol. 1972 Jan;93(1):42-8.
6
Malakoplakia of bone. An unusual cause of pathologic fracture in an immunosuppressed patient.骨嗜酸性粒细胞肉芽肿。免疫抑制患者病理性骨折的罕见病因。
Clin Orthop Relat Res. 1985 Dec(201):106-10.