Karlander L E, Lidman D, Franzén L
Department of Plastic Surgery, Hand Surgery and Burns, University Hospital, Linköping, Sweden.
Scand J Plast Reconstr Surg Hand Surg. 1994 Mar;28(1):19-23. doi: 10.3109/02844319409015990.
Thirty three rats were subjected to severe contusion of the femoral region by a heavy falling object. The injury was directed towards the palpated femoral vessels in a standard way as described in a previous study. One hour after the injury microvascular surgery was performed on the damaged part of the femoral artery. In 17 animals the artery was transected at the centre of the injured part. The ends were then anastomosed without resection. In the remaining 16 animals the damaged part of the artery was resected and a long arterial graft taken from the opposite, uninjured leg was substituted. Postoperatively the animals were observed for two hours. Arterial patency was evaluated immediately after injury, at the end of operation and after one and two hours. After the animals had been killed, transverse sections of the damaged arteries from 28 of the 33 were examined by light microscopy. Signs of severe contusion was found in 82% of the specimens. The overall number of injured arteries was 97%. The patency rate after transection treated by direct suture was 71%, and after resection and vascular grafting it was 100%.
33只大鼠受到重物坠落导致的严重股骨区域挫伤。按照先前研究中描述的标准方式，损伤针对可触及的股血管。损伤后1小时，对股动脉受损部位进行微血管手术。17只动物的动脉在损伤部位中央横断。然后在不切除的情况下将两端吻合。其余16只动物切除动脉受损部分，并用取自对侧未受伤腿部的一段长动脉移植物进行替代。术后对动物观察2小时。在损伤后、手术结束时以及1小时和2小时后评估动脉通畅情况。处死动物后，对33只中的28只受损动脉的横切片进行光学显微镜检查。82%的标本发现有严重挫伤迹象。受损动脉的总数为97%。直接缝合横断处理后的通畅率为71%，切除并血管移植后的通畅率为100%。
