急性冠状动脉闭塞期间的心内膜下S-T段改变。
Subendocardial S-T segment changes during acute coronary occlusion.
作者信息
Guyton R A
机构信息
Clinic of Surgery, National Heart and Lung Institute, Bethesda, Md. 20014.
出版信息
Ann Thorac Surg. 1975 Jul;20(1):52-5. doi: 10.1016/s0003-4975(10)63852-0.
Subendocardial ischemia during coronary occlusion in dogs was studied using S-T segment elevations in unipolar subendocardial electrodes. Alterations in heart rate or cardiac output caused quantitatively similar changes in subendocardial and epicardial S-T elevation. Increasing blood pressure from 75 to 100 or 75 to 125 mm Hg caused a smaller reduction in subendocardial than in epicardial S-T elevation (p less than 0.01). In this situation, therefore, subendocardial ischemia tends to be maintained while epicardial ischemia is reduced by higher arterial pressures. Hemodynamic manipulations can cause quantitatively different changes in subendocardial and epicardial S-T segment elevation.
利用单极心内膜下电极的S-T段抬高，对犬冠状动脉闭塞期间的心内膜下缺血进行了研究。心率或心输出量的改变在心内膜下和心外膜S-T段抬高方面引起了数量上相似的变化。将血压从75毫米汞柱升高到100毫米汞柱或从75毫米汞柱升高到125毫米汞柱时，心内膜下S-T段抬高的降低幅度小于心外膜S-T段抬高的降低幅度（p<0.01）。因此，在这种情况下，心内膜下缺血倾向于持续存在，而心外膜缺血则因较高的动脉压而减轻。血流动力学操作可在心内膜下和心外膜S-T段抬高方面引起数量上不同的变化。
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