Hanly M G, Allsbrook W C, Pantazis C G, Lane R, Porubsky E S, Mann E S
Department of Pathology, University of Texas, M. D. Anderson Cancer Center, Houston.
Am J Dermatopathol. 1994 Apr;16(2):196-200. doi: 10.1097/00000372-199404000-00018.
We report a case of malignant pilomatrixoma with a pronounced biphenotypic morphology. The lesion, which was excised from the cheek of a 36-year-old man, was composed of a large pilomatrixoma lying within a spindled, sarcomatoid stroma. Fourteen months later, the tumor metastasized to the right upper lobe of the lung. We describe the tumor's pathology, histology, and immunochemistry and discuss the differential diagnosis. We also speculate on its histogenesis.
我们报告一例具有明显双相形态的恶性毛母质瘤。该病变取自一名36岁男性的脸颊，由一个位于梭形、肉瘤样间质内的大型毛母质瘤组成。14个月后，肿瘤转移至右肺上叶。我们描述了肿瘤的病理学、组织学和免疫化学，并讨论了鉴别诊断。我们还推测了其组织发生。
