Ionescu N, Onicescu D, Muşat S, Trifan O C
Department of Cell Biology and Histology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Rom J Morphol Embryol. 1993 Jan-Jun;39(1-2):9-11.
The synthesis and the release of the atrial natriuretic factor (ANF) were studied by electron microscopy in the atrial cells from an ischemic myocardium. The ANF-containing secretory vesicles of normal atrial cells were present in great number near the Golgi apparatus, and near the sarcolemma. After 30 min. of global ischemia the number of ANF-containing secretory vesicles decreased in the atrial cells, suggesting an ANF release during heart ischemia.
采用电子显微镜研究了缺血心肌心房细胞中心房利钠因子(ANF)的合成与释放。正常心房细胞中含ANF的分泌囊泡大量存在于高尔基体附近和肌膜附近。全心缺血30分钟后,心房细胞中含ANF的分泌囊泡数量减少,提示心脏缺血期间有ANF释放。