嗜亲性宿主范围小鼠逆转录病毒的细胞表面受体：一种阳离子氨基酸转运体。
Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter.
作者信息
Kavanaugh M P, Wang H, Boyd C A, North R A, Kabat D
机构信息
Department of Biochemistry, Oregon Health Sciences, University Portland.
出版信息
Arch Virol Suppl. 1994;9:485-94. doi: 10.1007/978-3-7091-9326-6_47.
The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.
嗜亲性宿主范围小鼠白血病病毒的细胞表面受体是一种对必需阳离子酸不依赖钠的转运体。我们的证据有力地表明该受体就是转运体系统y+，它先前是通过转运测定来表征的。突变分析表明转运体活性对于病毒接收并非必需。用嗜亲性逆转录病毒感染细胞仅会导致细胞表面受体表达的部分下调。
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