• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

酵母乙醇脱氢酶与伯脂肪醇和醛的动力学机制。

Kinetic mechanism of yeast alcohol dehydrogenase with primary aliphatic alcohols and aldehydes.

作者信息

Trivić S, Leskovac V

机构信息

Faculty of Sciences, Bulevar Cara Lazara, Novi Sad, Yogoslavia.

出版信息

Biochem Mol Biol Int. 1994 Mar;32(3):399-407.

PMID:8032309
Abstract

Yeast alcohol dehydrogenase (EC 1.1.1.1) catalyzes the interconversion of three redox pairs, ethanol/acetaldehyde, propanol/propionaldehyde and butanol/butyraldehyde by the same common mechanism, only with different magnitudes of rate constants. This general mechanism is Ordered Bi Bi in both directions, with the formation of abortive ternary complexes enzyme.NAD+.aldehyde and binary complexes enzyme.aldehyde.

摘要

酵母乙醇脱氢酶(EC 1.1.1.1)通过相同的通用机制催化三种氧化还原对(乙醇/乙醛、丙醇/丙醛和丁醇/丁醛)的相互转化,只是速率常数的大小不同。这种通用机制在两个方向上都是有序的双双反应机制,会形成无活性的三元复合物酶·NAD⁺·醛以及二元复合物酶·醛。

相似文献

1
Kinetic mechanism of yeast alcohol dehydrogenase with primary aliphatic alcohols and aldehydes.酵母乙醇脱氢酶与伯脂肪醇和醛的动力学机制。
Biochem Mol Biol Int. 1994 Mar;32(3):399-407.
2
Use of pH studies to determine the kinetic and chemical mechanism of yeast alcohol dehydrogenase with primary aliphatic alcohols and aldehydes.利用pH研究确定酵母乙醇脱氢酶与伯脂肪醇和醛的动力学及化学机制。
Indian J Biochem Biophys. 1996 Jun;33(3):177-83.
3
Kinetic mechanism of yeast alcohol dehydrogenase activity with secondary alcohols and ketones.酵母乙醇脱氢酶对仲醇和酮的催化动力学机制
Indian J Biochem Biophys. 1994 Oct;31(5):387-91.
4
A method for the characterization of aldehyde dehydrogenase with use of alcohol dehydrogenase.一种利用乙醇脱氢酶对乙醛脱氢酶进行表征的方法。
Res Commun Chem Pathol Pharmacol. 1987 Nov;58(2):257-67.
5
Redox-elimination reaction catalyzed by yeast alcohol dehydrogenase.酵母乙醇脱氢酶催化的氧化还原消除反应
Biochem Int. 1991 Nov;25(4):669-75.
6
Drosophila melanogaster alcohol dehydrogenase: mechanism of aldehyde oxidation and dismutation.黑腹果蝇乙醇脱氢酶:醛氧化和歧化机制
Biochem J. 1998 Feb 1;329 ( Pt 3)(Pt 3):561-70. doi: 10.1042/bj3290561.
7
Structure and function in yeast alcohol dehydrogenases.酵母乙醇脱氢酶的结构与功能
Prog Clin Biol Res. 1987;232:227-36.
8
The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography.果蝇乙醇脱氢酶的催化反应与抑制机制:通过X射线晶体学以1.4埃分辨率观察酶结合的NAD-酮加合物
J Mol Biol. 1999 Jun 4;289(2):335-55. doi: 10.1006/jmbi.1999.2765.
9
A study of the kinetics and mechanism of yeast alcohol dehydrogenase with a variety of substrates.一项关于酵母乙醇脱氢酶与多种底物的动力学及作用机制的研究。
Biochem J. 1973 Feb;131(2):261-70. doi: 10.1042/bj1310261.
10
Substrate specificity of human and yeast aldehyde dehydrogenases.人和酵母醛脱氢酶的底物特异性
Chem Biol Interact. 2009 Mar 16;178(1-3):36-9. doi: 10.1016/j.cbi.2008.10.002. Epub 2008 Oct 15.

引用本文的文献

1
Kinetics of ethanol oxidation catalyzed by yeast alcohol dehydrogenase in aqueous solutions of sodium dodecylsulfate.酵母乙醇脱氢酶在十二烷基硫酸钠水溶液中催化乙醇氧化的动力学
Protein J. 2008 Jun;27(4):247-52. doi: 10.1007/s10930-008-9131-6.
2
A general method for the analysis of random bisubstrate enzyme mechanisms.一种分析随机双底物酶机制的通用方法。
J Ind Microbiol Biotechnol. 2004 May;31(4):155-60. doi: 10.1007/s10295-004-0128-7. Epub 2004 Apr 27.
3
Use of competitive dead-end inhibitors to determine the chemical mechanism of action of yeast alcohol dehydrogenase.
使用竞争性终产物抑制剂来确定酵母乙醇脱氢酶的化学作用机制。
Mol Cell Biochem. 1998 Jan;178(1-2):219-27. doi: 10.1023/a:1006851816483.