Tel'nov V I
Klin Lab Diagn. 1994(1):35-7.
Haptoglobin (Hp) phenotypes were determined in 646 subjects aged 25 to 76. Hp phenotype distribution in the examinees (13.6% for type 1-1; 49.4% for type 2-1; and 37.0% for type 2-2) was found as expected. Levels of eighteen metabolic, enzymatic, hormonal, and immunologic blood serum parameters were studied in subjects with various Hp phenotypes. Elevated levels of uric acid (by 12%, p < 0.01) and lactate dehydrogenase activity (by 7%, p < 0.05) in Hp 1-1 type were revealed as against other Hp types. A higher uric acid level in Hp 1-1 type was found in subjects of different age and both sexes, whereas LDH activity elevation was observed only in men aged over 55.
对646名年龄在25岁至76岁之间的受试者进行了触珠蛋白（Hp）表型测定。受检者中Hp表型分布（1-1型为13.6%；2-1型为49.4%；2-2型为37.0%）符合预期。对具有不同Hp表型的受试者的18种代谢、酶、激素和免疫血清参数水平进行了研究。与其他Hp类型相比，发现Hp 1-1型的尿酸水平升高（升高12%，p<0.01）以及乳酸脱氢酶活性升高（升高7%，p<0.05）。在不同年龄和性别的受试者中均发现Hp 1-1型的尿酸水平较高，而仅在55岁以上的男性中观察到乳酸脱氢酶活性升高。
