Yamashita Y, Harada M, Yamamoto H, Miyazaki T, Takahashi M, Miyazaki K, Okamura H
Department of Radiology, Kumamoto University School of Medicine, Japan.
Br J Radiol. 1994 Jun;67(798):530-4. doi: 10.1259/0007-1285-67-798-530.
32 patients with uncontrollable genital bleeding resulting from postpartum haemorrhage (n = 15) or malignant neoplasms (n = 17) were treated by arterial embolization therapy on an emergency basis. The 15 patients with postpartum haemorrhage responded dramatically to treatment by embolization. Follow-up computed tomography or magnetic resonance studies in 12 cases showed haematomas in the pelvic extraperitoneal space, but most then reduced in size or disappeared spontaneously. In two patients with large haematomas, laparotomy was required. No serious complications developed and normal menstruation resumed in the women who did not undergo hysterectomy. In the 17 patients with malignant neoplasms, bleeding was temporally controlled in all, but recurred in seven and required re-embolization in three. One patient experienced slight numbness of the leg and another had a skin ulcer. All patients underwent subsequent treatment including radiation therapy (n = 10), operation (n = 5) or chemotherapy (n = 2). We conclude that arterial embolization has significant merits in the management of patients with uncontrollable genital bleeding.
32例因产后出血(n = 15)或恶性肿瘤(n = 17)导致无法控制的生殖器出血的患者接受了紧急动脉栓塞治疗。15例产后出血患者对栓塞治疗反应显著。12例患者的随访计算机断层扫描或磁共振研究显示盆腔腹膜外间隙有血肿,但大多数随后体积缩小或自行消失。2例有大血肿的患者需要进行剖腹手术。未发生严重并发症,未行子宫切除术的女性恢复了正常月经。在17例恶性肿瘤患者中,所有患者的出血均得到暂时控制,但7例复发,3例需要再次栓塞。1例患者出现腿部轻微麻木,另1例有皮肤溃疡。所有患者均接受了后续治疗,包括放疗(n = 10)、手术(n = 5)或化疗(n = 2)。我们得出结论,动脉栓塞在治疗无法控制的生殖器出血患者方面具有显著优点。