Chmelik F, Flaherty D K, Reed C E
Am Rev Respir Dis. 1975 Feb;111(2):201-5. doi: 10.1164/arrd.1975.111.2.201.
The frequency of precipitating antibodies to Aspergillus, thermophilic actinomycetes, and pigeon serum was studied in hospitalized patients and in employees of the state of Wisconsin. Precipitins to Aspergillus were detected in 9 per cent of the hospitalized patients and 3 per cent of the state employees. The majority of the serologically reactive hospitalized patients were diagnosed as having carcinoma with metastases, lymphoma, or leukemia. No evidence of hypersensitivity pneumonitis or invasive aspergillosis was seen in these patients. The frequency of antibodies to thermophilic actinomycetes (3 per cent) and pigeon serum (1 per cent) was similar in both groups. Women from 17 to 25 years of age and men from 52 to 66 years of age demonstrated an increased incidence of positive precipitins.
对威斯康星州住院患者和该州雇员体内针对曲霉菌、嗜热放线菌及鸽血清沉淀抗体的频率进行了研究。在9%的住院患者和3%的该州雇员体内检测到了针对曲霉菌的沉淀素。大多数血清学反应呈阳性的住院患者被诊断患有伴有转移的癌症、淋巴瘤或白血病。在这些患者中未发现过敏性肺炎或侵袭性曲霉菌病的证据。两组中针对嗜热放线菌(3%)和鸽血清(1%)的抗体频率相似。17至25岁的女性和52至66岁的男性沉淀素阳性发生率有所增加。