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Sexual precocity in Klinefelter syndrome: report on two new cases with idiopathic central precocious puberty.

作者信息

von Mühlendahl K E, Heinrich U

机构信息

Kinderhospital Osnabrück, Germany.

出版信息

Eur J Pediatr. 1994 May;153(5):322-4. doi: 10.1007/BF01956410.

DOI:10.1007/BF01956410
PMID:8033919
Abstract

Precocious puberty apparently occurs more often in boys with Klinefelter syndrome than could be expected by chance. So far, reports exist on nine such patients, to which two more cases are added here. Whereas most of the previously described boys had endocrinologically active tumours, these two patients had sexual precocity of the idiopathic type.

摘要

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Klinefelter syndrome, tumor, and sexual precocity.克兰费尔特综合征、肿瘤与性早熟。
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Idiopathic central precocious puberty in a Klinefelter patient: highlights on gonadotropin levels and pathophysiology.克兰费尔特综合征患者的特发性中枢性性早熟:促性腺激素水平及病理生理学要点
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Central precocious puberty as a prelude to hypogonadism in a patient with Klinefelter syndrome.

本文引用的文献

1
[Klinefelter's syndrome associated with precocious puberty due to tumoral secretion of chorionic gonadotropins].[克氏综合征伴绒毛膜促性腺激素肿瘤分泌所致性早熟]
Arch Fr Pediatr. 1981 Feb;38(2):129-32.
2
Klinefelter syndrome, tumor, and sexual precocity.克兰费尔特综合征、肿瘤与性早熟。
J Pediatr. 1980 Oct;97(4):607-9. doi: 10.1016/s0022-3476(80)80021-7.
3
The association of congenital malformations and malignant tumors in infants and children.婴幼儿先天性畸形与恶性肿瘤的关联。
克氏综合征患者中枢性性早熟作为性腺功能减退的前奏。
Pediatr Investig. 2019 Jun 25;3(2):127-130. doi: 10.1002/ped4.12136. eCollection 2019 Jun.
4
Central precocious puberty as a prelude of gonad dysplasia.中枢性性早熟作为性腺发育异常的前奏。
Pediatr Investig. 2019 Mar 22;3(1):50-54. doi: 10.1002/ped4.12118. eCollection 2019 Mar.
5
Central precocious puberty and abnormal chromosomal patterns.中枢性性早熟与异常染色体模式。
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Ann Clin Lab Sci. 1974 Sep-Oct;4(5):363-71.
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Testicular germ cell tumor in patient with Klinefelter syndrome.克兰费尔特综合征患者的睾丸生殖细胞肿瘤
Urology. 1988 Jan;31(1):72-4. doi: 10.1016/0090-4295(88)90579-1.
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Precocious puberty associated with malignant thoracic teratoma and malignant histiocytosis in a child with Klinefelter's syndrome.
Med Pediatr Oncol. 1987;15(5):277-80. doi: 10.1002/mpo.2950150511.
6
[Mediastinal teratocarcinoma and hypophyseal stalk germinoma in a patient with Klinefelter syndrome].
Klin Padiatr. 1990 Jan-Feb;202(1):53-6. doi: 10.1055/s-2007-1025486.
7
[Klinefelter's syndrome. Trilogy of Fallot. Teratoma of the mediastinum and early puberty].[克兰费尔特综合征。法洛四联症。纵隔畸胎瘤与性早熟]
Pediatrie. 1975 Mar;30(2):185-92.
8
Sexual precocity and thoracic polyembryoma: Klinefelter syndrome?性早熟与胸部多胚瘤:克兰费尔特综合征?
J Pediatr. 1979 Jan;94(1):163. doi: 10.1016/s0022-3476(79)80393-5.