The MLLT3 gene maps between D9S156 and D9S171 and contains an unstable polymorphic trinucleotide repeat.
作者信息
Walker G J, Walters M K, Palmer J M, Hayward N K
机构信息
Queensland Cancer Fund Research Unit, Queensland Institute of Medical Research, Herston, Australia.
出版信息
Genomics. 1994 Apr;20(3):490-1. doi: 10.1006/geno.1994.1206.
PMID:8034324
Abstract
MLLT3, one of the genes shown to be a translocation breakpoint partner for the acute lymphocytic leukemia (MLL) gene, has been mapped to 9p22. We have identified a polymorphic trinucleotide repeat within this gene that shows somatic instability. The inheritance pattern of this polymorphism in recombinant individuals from families previously typed for other chromosome 9 markers indicates that the gene lies in the interval bounded by D9S156 and D9S171.
摘要
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